AMID-DERIVATE UND DEREN MEDIZINISCHE VERWENDUNG

The present invention relates to a compound of the formula wherein R is substituted aryl, heteroaryl and the like, R and R are hydrogen, alkyl, halogen, hydroxyl group and the like, Q is N, CH and the like, W is hydrogen, alkyl, hydroxycarbonylalkyl and the like, X is halogen, cyano, nitro, amino an...

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Hauptverfasser: NAKA YOICHI, KAWAGUCHI, TAKAFUMI, CHIBA, KENJI, USHIO, HIROYUKI, ISHIBUCHI SEIGO, SUGIYAMA, NAOKI, OHTSUKI, MAKIO, ISHIBUCHI, SEIGO, NAITO, YOUICHIRO, OHTSUKI MAKIO, CHIBA KENJI, NAKA, YOICHI
Format: Patent
Sprache:ger
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Zusammenfassung:The present invention relates to a compound of the formula wherein R is substituted aryl, heteroaryl and the like, R and R are hydrogen, alkyl, halogen, hydroxyl group and the like, Q is N, CH and the like, W is hydrogen, alkyl, hydroxycarbonylalkyl and the like, X is halogen, cyano, nitro, amino and the like, X' is hydrogen, halogen, cyano, nitro, and Y is alkyl, hydroxyl group, alkoxy, mercapto and the like and a salt thereof, and a medicine containing the said compound. The compound of the present invention shows a superior inhibitory effect on activated lymphocytes proliferation and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.