VERFAHREN ZUR ALKYLIERUNG VON GEHINDERTEN SULFONAMIDEN, DIE ZUR HERSTELLUNG VON METALLPROTEINASEHEMMER GEEIGNET SIND

The present invention relates to a process for the preparation of compounds of formula (b), in which a compound of formula V is reacted with a compound of formula VI. The resulting compound of formula IV is reduced to a compound of formula III which is hydrolysed to a compound of formula (b). Altern...

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Bibliographische Detailangaben
Hauptverfasser:	HAWKINS, JOEL, MICHAEL, ANDRESEN, BRIAN, MICHAEL, HAMMEN, PHILIP, DIETRICH
Format:	Patent
Sprache:	ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR RELEVANT APPARATUS TRANSPORTING
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Beschreibung
Zusammenfassung:	The present invention relates to a process for the preparation of compounds of formula (b), in which a compound of formula V is reacted with a compound of formula VI. The resulting compound of formula IV is reduced to a compound of formula III which is hydrolysed to a compound of formula (b). Alternatively, a compound of formula IV is hydrolysed to a compound of formula (a) which reduced to a compound of formula (b). Compounds of formula IV are novel. In the formulae the variables are as defined in the claims.