ALPHA-SUBSTITUIERUNG VON UNGESCHÜTZTEN BETA- AMINOESTERN

Methods for stereoselective substitution in which a (mono or un)-alpha-substituted unprotected beta-amino ester compound or salt thereof is reacted with an aliphatic electrophile in the presence of a base selected from alkyl lithium compounds, lithium hydride, lithium amide, lithium dialkyl amides a...

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Hauptverfasser: CHANDRAMOULI, SITHAMALLI, V, O'BRIEN, MICHAEL, K, POWNER, TORY, H
Format: Patent
Sprache:ger
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Zusammenfassung:Methods for stereoselective substitution in which a (mono or un)-alpha-substituted unprotected beta-amino ester compound or salt thereof is reacted with an aliphatic electrophile in the presence of a base selected from alkyl lithium compounds, lithium hydride, lithium amide, lithium dialkyl amides and alkali hexamethyldisilylamines.