QUERVERNETZTE STÄRKE MIT HOHEM AMYLOSEANTEIL UND FUNKTIONELLEN GRUPPEN ALS MATRIX FÜR LANGSAME FREISETZUNG PHARMAZEUTISCHER WIRKSTOFFE

The present invention is concerned with a solid slow release oral pharmaceutical dosage unit resistant to amylase which comprises a solid dosage unit made up of an admixture of a therapeutic dosage of an orally effective pharmaceutical product, an optional polysaccharide or polyol, and cross-linked...

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Hauptverfasser: ISPAS-SZABO, POMPILIA, LENAERTS, VINCENT, CHOUINARD, FRANCOIS, MATEESCU, MIRCEA A
Format: Patent
Sprache:ger
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Zusammenfassung:The present invention is concerned with a solid slow release oral pharmaceutical dosage unit resistant to amylase which comprises a solid dosage unit made up of an admixture of a therapeutic dosage of an orally effective pharmaceutical product, an optional polysaccharide or polyol, and cross-linked high amylose starch, wherein the cross-linking of the high amylose starch has been carried out with a covalent or non-covalent cross-linking agent with from about 0.1 g to about 30 g of cross-linking agent per 100 g of high amylose starch.