DIREKTKOMPRIMIERTE PARTIKEL FÜR FESTE DARREICHUNGSFORMEN

Solid dosage articles such as pharmaceutical tablets for the controlled release of a desired compound such as an active ingredient are directly compressed from a flowable, compressible mixture of the active ingredient, a slightly cross-linked rheology modifying polymer or copolymer, and one or more...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WILBER, WILLIAM, R, GREENBERG, EDWARD, S, GUO, JIAN-HWA
Format: Patent
Sprache:ger
Schlagworte:
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Beschreibung
Zusammenfassung:Solid dosage articles such as pharmaceutical tablets for the controlled release of a desired compound such as an active ingredient are directly compressed from a flowable, compressible mixture of the active ingredient, a slightly cross-linked rheology modifying polymer or copolymer, and one or more excipients. The rheology modifying polymer or copolymer is a granulated powder of suitable particle size and is generally made from one or more unsaturated (di)carboxylic acids, half ester thereof, and other optional monomers.