PDE IV-INHIBITOREN ZUR BEHANDLUNG DER MULTIPLEN SKLEROSE

PDE IV-INHIBITOREN ZUR BEHANDLUNG DER MULTIPLEN SKLEROSE

The present invention is a method of preventing or ameliorating the episodic recurrence of MS, comprising administering an effective amount of selective phosphodiesterase inhibitors of Type IV, e.g., Rolipram, e.g., wherein the severity of the episodic recurrences is ameliorated or the time period b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HEDGPETH, JOEL, LOESCHMANN, PETER-ANDREAS, GRAF, HERMANN, WACHTEL, HELMUT, SCHMIECHEN, RALPH, PEREZ, H.DANIEL
Format: Patent
Sprache:ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention is a method of preventing or ameliorating the episodic recurrence of MS, comprising administering an effective amount of selective phosphodiesterase inhibitors of Type IV, e.g., Rolipram, e.g., wherein the severity of the episodic recurrences is ameliorated or the time period between episodes is lengthened. The present invention also relates to a pharmaceutical composition for treating MS comprising an effective amount of a combination of a PDE IV inhibitor and an anti-inflammatory or immunomodulatory drug in a pharmaceutically acceptable carrier.