SELEKTIVE ANALOGE DER THYROIDHORMONE

Selective thyroid hormone agonists are disclosed that are highly selective for the TR beta subtype with high binding affinity. Methods of using such agonists and pharmaceutical compositions containing them are also disclosed, as are novel procedures for their preparation.

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Bibliographische Detailangaben
Hauptverfasser: YOSHIHARA, HIKARI, CHELLINI, GRAZIA, BAXTER, JOHN, D, RIBEIRO, RALFF C.J, APRILETTI, JAMES, SCANLAN, THOMAS, S
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:Selective thyroid hormone agonists are disclosed that are highly selective for the TR beta subtype with high binding affinity. Methods of using such agonists and pharmaceutical compositions containing them are also disclosed, as are novel procedures for their preparation.