SCHNITTSTELLE FÜR IONTOPHORESE

A hydrophilic membrane having a low adsorptivity for a protein is disposed, as an interface, in a side to be contacted with a skin, and a drug such as a physiologically active peptide is transdermally delivered by iontophoresis. The membrane has an adsorptivity for a protein of not greater than 10 m...

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Bibliographische Detailangaben
Hauptverfasser: MATSUMOTO, YUKIHIRO, YANAI, SHIGEO, IGA, KATSUMI, HIGO, NARUHITO
Format: Patent
Sprache:ger
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Zusammenfassung:A hydrophilic membrane having a low adsorptivity for a protein is disposed, as an interface, in a side to be contacted with a skin, and a drug such as a physiologically active peptide is transdermally delivered by iontophoresis. The membrane has an adsorptivity for a protein of not greater than 10 mu g/cm . The thickness of the membrane is about 10 to 200 mu m and the porosity of the membrane is about 60 to 90%. Such membrane includes a hydrophilized fluororesin membrane, a hydrophilized polysulfone membrane and a hydrophilized cellulose derivative membrane.