4-PHENYL-3-SUBSTITUIERTE 1,4-DIHYDROPYRIDINESTER MIT CEREBRALER AKTIVITÄT

4-Phenyl 3-substituted 1,4-dihydropyridine esters are prepared by reacting benzaldehydes with keto esters and enamines, where appropriate with isolation of ylidene intermediates, or by esterification of corresponding dihydropyridinecarboxylic acids with alcohols. The 4-phenyl 3-substituted 1,4-dihyd...

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Hauptverfasser: GAO, ZHAN DR, SCHOHE-LOOP, RUDOLF DR, MEIER, HEINRICH DR, SCHUURMAN, TEUNIS DR, HARTWIG, WOLFGANG DR, JUNGE, BODO DR, DE JONGE, MAARTEN DR, SCHMIDT, BERNARD DR
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Sprache:ger
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Zusammenfassung:4-Phenyl 3-substituted 1,4-dihydropyridine esters are prepared by reacting benzaldehydes with keto esters and enamines, where appropriate with isolation of ylidene intermediates, or by esterification of corresponding dihydropyridinecarboxylic acids with alcohols. The 4-phenyl 3-substituted 1,4-dihydropyridine esters can be used as active ingredients in pharmaceuticals for the treatment of the central nervous system, in particular as cerebral therapeutic agents.