VERFAHREN ZUR DIAGNOSE VON DIABETES UND PRAEDIABETISCHER BEDINGUNGEN

PCT No. PCT/AU94/00056 Sec. 371 Date Oct. 10, 1995 Sec. 102(e) Date Oct. 10, 1995 PCT Filed Feb. 9, 1994 PCT Pub. No. WO94/18568 PCT Pub. Date Aug. 18, 1994A method for detecting autoantibodies to glutamic acid decarboxylase (GAD) in the serum of a patient as diagnostic of a diabetic or prediabetic...

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Hauptverfasser:	ROWLEY, MERRILL, JOY, ZIMMET, PAUL, ZEV, MACKAY, IAN, REAY
Format:	Patent
Sprache:	ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Zusammenfassung:	PCT No. PCT/AU94/00056 Sec. 371 Date Oct. 10, 1995 Sec. 102(e) Date Oct. 10, 1995 PCT Filed Feb. 9, 1994 PCT Pub. No. WO94/18568 PCT Pub. Date Aug. 18, 1994A method for detecting autoantibodies to glutamic acid decarboxylase (GAD) in the serum of a patient as diagnostic of a diabetic or prediabetic condition in the patient, comprises contacting a serum sample from the patient with a GAD antigen and detecting binding of autoantibodies to GAD in the sample by the GAD antigen, wherein the GAD antigen comprises a GAD preparation containing an enhanced amount of dimer(s) or oligomer(s) of the 65 kD or 67 kD isoforms, or both, of GAD. A diagnostic kit is also inclosed.