SUBSTITUIERTE HETEROCYCLISCHE BENZOCYCLOALKENE UND IHRE VERWENDUNG ALS ANALGETISCH WIRKSAME SUBSTANZEN

Aminomethyl substituted heterocyclic benzocycloalkene derivatives (I) are new. Aminomethyl substituted heterocyclic benzocycloalkene derivatives of formula (I) and their salts are new: R = OH; 1-6C alkoxy; or 3-7C cycloalkyloxy; R = 1-6C alkyl; R = 1-6C alkyl; aryl-1-2C alkyl; heterocyclyl-1-2C alky...

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Bibliographische Detailangaben
Hauptverfasser:	PUETZ, CLAUDIA DR, STRASSBURGER, WOLFGANG DR, ZIMMER, OSWALD DR, ENGLBERGER, WERNER DR, KOEGEL, BABETTE-YVONNE DR
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Aminomethyl substituted heterocyclic benzocycloalkene derivatives (I) are new. Aminomethyl substituted heterocyclic benzocycloalkene derivatives of formula (I) and their salts are new: R = OH; 1-6C alkoxy; or 3-7C cycloalkyloxy; R = 1-6C alkyl; R = 1-6C alkyl; aryl-1-2C alkyl; heterocyclyl-1-2C alkyl; -CH2-CH=C(R )2; or 3-7C cycloalkyl-methyl; R , R = H; Cl; F; CF3; 1-6C alkyl; OH; 1-6C alkoxy; 3-7C cycloalkyloxy; alpha , beta or beta , gamma -O-(CH2)o-O-; -(CH2)n-aryl; heterocyclyl; -O-(CH2)n-aryl; or alpha , beta - or beta , gamma -benzo optionally mono- or disubstituted by F, Cl, CF3, OH, 1-6C alkyl, 1-6C alkoxy or -CON(R R ); R = H or 1-6C alkyl; R = H; 1-6C alkyl; -(CH2)naryl; or CH2-3-7C cycloalkyl; or R + R = -(CH2)m or -(CH2)2-O-(CH2)2-; X = O; S; SO; or SO2; Y = -(CH2)0; -CH2-C(CH3)2-; or -C(CH3)2-; n = 0-2; m = 5-7; o = 1-2. An Independent claim is included for the preparation of compounds (I).