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Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula I: wherein: R' is hydrogen, methyl or NH2C(O)CH2-; R'' and R''' are independently methyl or hydrogen; R, R, R, R, R, and R are independently hyd...

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Bibliographische Detailangaben
Hauptverfasser:	RODRIGUEZ, MICHAEL JOHN, JAMISON, JAMES ANDREW, 1C, BORROMEO, PETER STANLEY, VASUDEVAN, VENKATRAGHAVAN, TURNER, WILLIAM WILSON, JR
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula I: wherein: R' is hydrogen, methyl or NH2C(O)CH2-; R'' and R''' are independently methyl or hydrogen; R, R, R, R, R, and R are independently hydroxy or hydrogen; R0 is a group of the formula R1 is C1-C6 alkyl, C1-C6 alkoxy, phenyl, p-halo-phenyl, p-nitrophenyl, phenoxy, benzyl, p-halo-benzyl, or p-nitro-benzyl; and R2 is an acyl side chain as defined herein.