ANTIKOAGULIEREND WIRKENDE PEPTIDYL-ARGININ ALDEHYD DERIVATE

The invention relates to new peptidyl-arginine aldehyde compounds of formula (I)whereinQ represents an acyl group of formula Q'-OCO, wherein Q' represents an alkyl-group with 1-3 carbon atoms,D-Xaa represents a 3-cyclobutyl-D-alanyl- or 3-cyclopentyl-D-alanyl group,Pro represents an L-prol...

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Hauptverfasser:	JUHASZ, ATTILA, SZELL, ERZSEBET, BARABAS, EVA, SZEKER, AGNES, BAJUSZ, SANDOR, LAVICH, EMILIA, TASCHLER, ZSUZSANNA, MAKK, KLARA, KASZAS, EVA, MORAVCSIK, IMRE, FEHER, ANDRAS, SZABO, GABRIELLA, LANGO, JUZSEF, TOTH, GABOR, MOHAI, ZSUZSANNA, SZALKAY, ANNA MARIA, VEGHELYI, IREN
Format:	Patent
Sprache:	ger
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Beschreibung
Zusammenfassung:	The invention relates to new peptidyl-arginine aldehyde compounds of formula (I)whereinQ represents an acyl group of formula Q'-OCO, wherein Q' represents an alkyl-group with 1-3 carbon atoms,D-Xaa represents a 3-cyclobutyl-D-alanyl- or 3-cyclopentyl-D-alanyl group,Pro represents an L-prolyl group, andArg represents an L-arginyl group,and acid-addition salts thereof, and pharmaceutical compositions comprising them, which are suitable for the prevention and cure of thrombosis and accelerated blood clotting.