VERFAHREN ZUR HERSTELLUNG VON 17-ESTERN VON

The invention provides an improved process for the preparation of 17-esters of 9 alpha ,21-dihalo-pregnane-11 beta ,17 alpha -diol-20-ones, and in particular for the preparation of 17-esters of anti-inflammatory steroids according to the above-mentioned scheme, wherein RCO, R , X, Y and the dotted l...

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Bibliographische Detailangaben
Hauptverfasser: TANN, CHOU-HONG, FU, XIAOYONG, KWOK, DAW-IONG, ALBERT, TSAI, DAVID, J., S
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:The invention provides an improved process for the preparation of 17-esters of 9 alpha ,21-dihalo-pregnane-11 beta ,17 alpha -diol-20-ones, and in particular for the preparation of 17-esters of anti-inflammatory steroids according to the above-mentioned scheme, wherein RCO, R , X, Y and the dotted line are as defined in the specification. The novel process is especially suitable for the preparation of Mometasone Furoate.