NEUE GLUCOCORTICOIDE

NEUE GLUCOCORTICOIDE

PCT No. PCT/EP94/00937 Sec. 371 Date Oct. 6, 1995 Sec. 102(e) Date Oct. 6, 1995 PCT Filed Mar. 24, 1994 PCT Pub. No. WO94/22898 PCT Pub. Date Oct. 13, 1994Glucocorticoids of general formula IR-Val-O-GC (II),are described, in which O-GC is the radical of a 21-hydroxycorticoid that has an antiinflamma...

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Hauptverfasser: ZENTEL, HANS JOACHIM, BRUMBY, THOMAS, ESPERLING, PETER, TOEPERT, MICHAEL, LAURENT, HENRY
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
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Zusammenfassung:PCT No. PCT/EP94/00937 Sec. 371 Date Oct. 6, 1995 Sec. 102(e) Date Oct. 6, 1995 PCT Filed Mar. 24, 1994 PCT Pub. No. WO94/22898 PCT Pub. Date Oct. 13, 1994Glucocorticoids of general formula IR-Val-O-GC (II),are described, in which O-GC is the radical of a 21-hydroxycorticoid that has an antiinflammatory action, Val represents a valine radical in the 21-position of the corticoid and R means a hydrogen atom or a hydrocarbon radical with up to 32 carbon atoms that is optionally substituted by hydroxy groups, amino groups, oxo groups and/or halogen atoms and/or interrupted by oxygen atoms, SO2 groups and/or NH groups and their salts.