MANGAN-KOMPLEXE MIT STICKSTOFF ENTHALTENDEN MAKROZYKLISCHEN LIGANDEN, WIRKSAM ALS SUPEROXIDDISMUTASEKATALYSATOREN
The present invention is directed to low molecular weight mimics of superoxide dismutase (SOD) represented by the formula: wherein R, R min , R1, R min 1, R2, R min 2, R3, R min 3, R4, R min 4, R5, R min 5, R6, R min 6, R7, R min 7, R8, R min 8, R9, and R min 9 and X, Y, Z and n are as defined herei...
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| creator | LENNON, PATRIC, JAMES NEUMAN, WILLIAM, LOJDA MODAK, ANIL, SHRIKRISHNA RILEY, DENNIS, PATRICK ASTON, KARL, WILLIAM WEISS, RANDY, HERMAN |
| description | The present invention is directed to low molecular weight mimics of superoxide dismutase (SOD) represented by the formula: wherein R, R min , R1, R min 1, R2, R min 2, R3, R min 3, R4, R min 4, R5, R min 5, R6, R min 6, R7, R min 7, R8, R min 8, R9, and R min 9 and X, Y, Z and n are as defined herein, useful as therapeutic agents for inflammatory disease states and disorders, ischemic/reperfusion injury, stroke, atherosclerosis, hypertension and all other conditions of oxidant-induced tissue damage or injury. |
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| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | MANGAN-KOMPLEXE MIT STICKSTOFF ENTHALTENDEN MAKROZYKLISCHEN LIGANDEN, WIRKSAM ALS SUPEROXIDDISMUTASEKATALYSATOREN |
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