MANGAN-KOMPLEXE VON STICKSTOFF-ENTHALTENDEN MACROZYKLISCHEN LIGANDEN UND IHRE VERWENDUNG ALS SUPEROXIDDISMUTASE KATALYSATOREN

The present invention is directed to low molecular weight mimics of superoxide dismutase (SOD) represented by the formula:wherein R, R', R1, R'1, R2, R'2, R3, R'3, R4, R'4, R5, R'5, R6, R'6, R7, R'7, R8, R'8, R9, R'10, R10 and R'10, X, Y, Z and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	LENNON, PATRICK, JAMES, MODAK, ANIL, SHRIKRISHNA, RILEY, DENNIS, PATRICK, ASTON, KARL, WILLIAM, NEUMANN, WILLIAM, LOJDA, WEISS, RANDY, HERMAN
Format:	Patent
Sprache:	ger
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention is directed to low molecular weight mimics of superoxide dismutase (SOD) represented by the formula:wherein R, R', R1, R'1, R2, R'2, R3, R'3, R4, R'4, R5, R'5, R6, R'6, R7, R'7, R8, R'8, R9, R'10, R10 and R'10, X, Y, Z and n are as defined herein, useful as therapeutic agents for inflammatory disease states and disorders, ischemic/reperfusion injury, myocardial infarction, stroke, atherosclerosis, and all other conditions of oxidant-induced tissue damage or injury.