NEUES VERFAHREN ZUR PRODUKTION VON NICHTFUSIONIERTEM PROTEIN IN E. COLI

A process for the preparation of a recombinant IGF-II (rIGF-II) without a covalently attached foreign protein moiety and without N-terminal attached methionine or a derivative of methionine or of a salt of said IGF-II, rIGF-II produced by said method, hybrid vectors comprising DNA encoding said rIGF...

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Bibliographische Detailangaben
Hauptverfasser: MAERKI, WALTER, SCHMITZ, ALBERT
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:A process for the preparation of a recombinant IGF-II (rIGF-II) without a covalently attached foreign protein moiety and without N-terminal attached methionine or a derivative of methionine or of a salt of said IGF-II, rIGF-II produced by said method, hybrid vectors comprising DNA encoding said rIGF-II, hosts transformed with said vectors, and a process for the isolation of said rIGF-II from the host cell and refolding it into a biologically active form.