VITAMIN-D-DERIVATE UND VERFAHREN ZUR HERSTELLUNG DIESER VERBINDUNGEN

VITAMIN-D-DERIVATE UND VERFAHREN ZUR HERSTELLUNG DIESER VERBINDUNGEN

The invention relates to a new vitamin D compound of the general formula wherein: R2 is a (C1-C3)alkyl group, a hydroxy(C1-C3)alkyl group, a (C1-C2)alkoxymethyl group or a (C2-C3)alkenyl or alkynyl group; R3 is a branched or non-branched, saturated or unsaturated aliphatic 3- to 5-membered hydrocarb...

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Bibliographische Detailangaben
Hauptverfasser: SESTELO, JOSE P, ZORGDRAGER, JAN, MOURINO, ANTONIO, VAN DE VELDE, JAN-PAUL, DIJKSTRA, GERHARDUS D. H, MASCARENAS, JOSE L, HALKES, SEBASTIANUS J
Format: Patent
Sprache:ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention relates to a new vitamin D compound of the general formula wherein: R2 is a (C1-C3)alkyl group, a hydroxy(C1-C3)alkyl group, a (C1-C2)alkoxymethyl group or a (C2-C3)alkenyl or alkynyl group; R3 is a branched or non-branched, saturated or unsaturated aliphatic 3- to 5-membered hydrocarbon or oxahydrocarbon biradical, having at least 3 atoms in the main chain and being optionally substituted with one or more substituents selected from epoxy, fluoro and hydroxy; iPr is an isopropyl group; and A and B are each individually hydrogen atoms or methyl groups, or A and B form together a methylene group. The invention further relates to a method of preparing these compounds and to their use in pharmacotherapy and cosmetics.