TEST, INDIKATOREN, IMMUNOGENE UND ANTIKÖRPER FÜR BENZODIAZEPINE

TEST, INDIKATOREN, IMMUNOGENE UND ANTIKÖRPER FÜR BENZODIAZEPINE

The present invention is directed to a fluorescence polarization assay for benzodiazepines and their metabolites, to the various components needed for preparing and carrying out such an assay and to methods of making these components. Specifically, tracers, immunogens and antibodies are disclosed, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HEIMAN, DANIEL FUELNER, KEEGAN, CANDACE LINDA, WANG, NAI-YI, FLENTGE, CHARLES ARTHUR, WANG, PHILIP PEI
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Beschreibung
Zusammenfassung:The present invention is directed to a fluorescence polarization assay for benzodiazepines and their metabolites, to the various components needed for preparing and carrying out such an assay and to methods of making these components. Specifically, tracers, immunogens and antibodies are disclosed, as well as methods for making them. The assay is conducted by measuring the degree of polarization retention of the fluorescence resulting when a sample mixed with antiserum and tracer is irradiated with plane polarized light.