DURCHFÜHRUNG EINES HOMOGENEN IMMUNOASSAYS NACH DEM AGGLUTINATIONSPRINZIP

DURCHFÜHRUNG EINES HOMOGENEN IMMUNOASSAYS NACH DEM AGGLUTINATIONSPRINZIP

A homogeneous immunoassay is performed according to the principle of agglutination using a) a conjugate which is obtained by an F(ab')2 fragment of an antibody of immunoglobulin class G being exposed to reducing conditions and subsequently reacted with component K which either has a functional...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BERGER, MICHAEL, DEGER, ARNO, GUILLOT, FRANCOIS
Format: Patent
Sprache:ger
Schlagworte:
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Beschreibung
Zusammenfassung:A homogeneous immunoassay is performed according to the principle of agglutination using a) a conjugate which is obtained by an F(ab')2 fragment of an antibody of immunoglobulin class G being exposed to reducing conditions and subsequently reacted with component K which either has a functional group suitable for binding or has been derivatised in a suitable manner by introducing a functional group, where component K is bound via the functional group to the free SH group, produced in the reduction, of the Fab' fragment, and b) particles which are capable of agglutination and which carry a substance able to bind to K.