VERBINDUNGEN ZUR EINFÜHRUNG EINER SH-GRUPPE IN TYROSIN

Compounds of the general formula in which A represents an amine-substituted aromatic radical and X represents a hydrocarbon radical having 1 to 10 carbon atoms, are prepared by reaction of a pyridyldithiocarbonic acid N-hydroxysuccinimide ester with the hydrazide of an aromatic carboxylic acid which...

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Bibliographische Detailangaben
Hauptverfasser: KLEIN, CHRISTIAN NAT, KIRCH, PETER NAT
Format: Patent
Sprache:ger
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Zusammenfassung:Compounds of the general formula in which A represents an amine-substituted aromatic radical and X represents a hydrocarbon radical having 1 to 10 carbon atoms, are prepared by reaction of a pyridyldithiocarbonic acid N-hydroxysuccinimide ester with the hydrazide of an aromatic carboxylic acid which is substituted by amine on the aromatic ring and are used for the introduction of an SH group into a tyrosine, in particular into a tyrosine or tyrosine derivative bonded in a peptide or protein.