VERFAHREN ZUR HERSTELLUNG NEUER BENZIMIDAZOL-DERIVATE UND IHRER SALZE
New benzimidazole derivatives of the general formula (I) and acid addition salts thereof, wherein R1 and R2 each represent hydrogen or methyl, R5 and R6 form together a valence bond and at the same time R3 and R4 form together a group of the general formula (II), -CH2-CH-CH2-NH-(CH2)n- ¦ (II) OH whe...
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Zusammenfassung: | New benzimidazole derivatives of the general formula (I) and acid addition salts thereof, wherein R1 and R2 each represent hydrogen or methyl, R5 and R6 form together a valence bond and at the same time R3 and R4 form together a group of the general formula (II), -CH2-CH-CH2-NH-(CH2)n- ¦ (II) OH wherein n is equal to zero or one, or R4, R5 and R6 form together a group of the formula (III) =N-CH2-CH-CH2- ¦ (III) OH and at the same time R3 stands for benzyl group, were prepared by reacting a compound of the general formula (IV), wherein R7 stands for hydrogen or benzyl group and R1, R2 and n each have the same meanings as defined above, or an acid addition salt thereof with epichlorohydrine optionally in the presence of a base. |
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