VERFAHREN ZUR HERSTELLUNG VON 2-GUANIDINOTHIAZOL- DERIVATEN

A method for preparing 2-guanidinothiazole derivs. of formula (I) comprises (A) reacting amidinothiourea of formua (II) with 1,3dihaloacetone to produce a cpd. of formula (III) (B) and then reacting (III) with thiourea in the pressence of water. In the formulas, Y is -C(NH2)NH; X is halogen. (I) act...

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Hauptverfasser: AGAI EVA, BOGSCH ERIK, BOD PETER, HARSANYI KALMAN.. DR, TRISCHLER FERENC DR
Format: Patent
Sprache:ger
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Zusammenfassung:A method for preparing 2-guanidinothiazole derivs. of formula (I) comprises (A) reacting amidinothiourea of formua (II) with 1,3dihaloacetone to produce a cpd. of formula (III) (B) and then reacting (III) with thiourea in the pressence of water. In the formulas, Y is -C(NH2)NH; X is halogen. (I) active against gastric acid secretion.