VERFAHREN ZUR HERSTELLUNG EINES STABILEN KRISTALLINEN DI- ODER TRIHYDRATS DER 7BETA((Z)-2-(2-AMINOTHIAZOL-4-YL)-4-CARBOXYBUT-2ENOYLAMINO)-3-CEPHEM-4-CARBONS|URE

VERFAHREN ZUR HERSTELLUNG EINES STABILEN KRISTALLINEN DI- ODER TRIHYDRATS DER 7BETA((Z)-2-(2-AMINOTHIAZOL-4-YL)-4-CARBOXYBUT-2ENOYLAMINO)-3-CEPHEM-4-CARBONS|URE

An antibacterial, 7 beta -[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-ca rboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule sealed by a band of gelatin to make a stable composi...

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Hauptverfasser: KAWATA KYOZO, SUZUKI YUSUKE, TAKEDA TOYOHIKO, TUJIKAWA MASANORI, SAKAMOTO TERUO, MINAMI KYOJI, HAMASHIMA YOSHIO
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:An antibacterial, 7 beta -[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-ca rboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule sealed by a band of gelatin to make a stable composition for clinical use after storage for a long time.