VERFAHREN ZUR HERSTELLUNG VON NEUEN THIAZOLIDIN-DERIVATEN

New thiazolidine compounds of the formula (I) having anti-ulcer activity are disclosed: (I) wherein Ar is a 2-furyl or a phenyl, naphthyl or pyridyl group optionally substituted by one or more C1-4-alkyl, C1-4-alkoxy, halo-C1-4-alkoxy, dihalomethyl, trihalomethyl, hydroxyl or nitro groups or by a gr...

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Hauptverfasser: HEGEDUES BELA DR, MATUZ JUDIT, EZER ELEMER, SZPORNY LASZLO DR, PALLAGI KATALIN, SZABADKAI ISTVAN, DOMANY GYOERGY DR, HARSANYI KALMAN DR, TETENYI PETER
Format: Patent
Sprache:ger
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Zusammenfassung:New thiazolidine compounds of the formula (I) having anti-ulcer activity are disclosed: (I) wherein Ar is a 2-furyl or a phenyl, naphthyl or pyridyl group optionally substituted by one or more C1-4-alkyl, C1-4-alkoxy, halo-C1-4-alkoxy, dihalomethyl, trihalomethyl, hydroxyl or nitro groups or by a group of the formula (II), (II) wherein Y is nitrogen or CH; Z is cyano or carbamoyl if Y is nitrogen, and represents a nitro group if Y is CH. Also disclosed are several processes for preparing the new compounds as well as pharmaceutical compositions and method of treatment employing same.