A process for the preparation of dispiro 1,2,4-trioxolane antimalarials 'OZ277'

A process for the preparation of dispiro 1,2,4-trioxolane antimalarials 'OZ277'

This invention relates to an improved process for the preparation of a compound of Formula (I), salts of the free base cis-adamantane-2-spiro-3'-8'-[[[(2'-amino-2'-methyl propyl)amino]carbonyl]methyl]-1',2',4'-trioxaspiro[4.5]decane wherein X can be an anion.

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Bibliographische Detailangaben
Hauptverfasser: DORWAL HARISH N, YADAV GYAN CHAND, VALAVALA SRINIVAS
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention relates to an improved process for the preparation of a compound of Formula (I), salts of the free base cis-adamantane-2-spiro-3'-8'-[[[(2'-amino-2'-methyl propyl)amino]carbonyl]methyl]-1',2',4'-trioxaspiro[4.5]decane wherein X can be an anion.