Encased tamper resistant controlled release dosageforms System and method for combining , packaging, and separating blended seed product

In certain embodiments, the present invention is directed to a solid controlled release dosage form comprising: a therapeutically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof dispersed in a controlled release excipient; wherein the inner 50% of the dosage form contai...

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Bibliographische Detailangaben
Hauptverfasser:	BOCKHAUS THOMAS RICHARD, DAVIS PAULA M, HUANG HAIYONG HUGH LZER WILLIAM A
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY FERTILISING FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE PERFORMING OPERATIONS PLANTING POSTAL SORTING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SEPARATING SOLIDS FROM SOLIDS SORTING SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTEDPIECE-MEAL, e.g. BY PICKING SOWING TRANSPORTING TRAPPING
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Beschreibung
Zusammenfassung:	In certain embodiments, the present invention is directed to a solid controlled release dosage form comprising: a therapeutically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof dispersed in a controlled release excipient; wherein the inner 50% of the dosage form contains at least 80% of the hydrocodone or salt thereof; wherein the amount of hydrocodone or salt thereof released from the dosage form is proportional within 20% to elapsed time from 8 to 24 hours, as measured by an in-vitro dissolution in a USP Apparatus 1 (basket) at 100 rpm in 900 ml simulated gastric fluid without enzymes (SGF) at 37°C.