2-(substituted-amino)-benzothiazole sulfonamide HIV protease inhibitors

The present invention relates to 2-(substituted-amino)-benzothiazole sulfonamide compounds and derivatives, their use as protease inhibitors, in particular as broad-spectrum HIV protease inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LAST STEFAAN JULIEN, DIERYNCK INGE, BAUMEISTER JUDITH EVA
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to 2-(substituted-amino)-benzothiazole sulfonamide compounds and derivatives, their use as protease inhibitors, in particular as broad-spectrum HIV protease inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising them. The present invention also concerns combinations of the present 2-(substituted-amino)-benzothiazole sulfonamide compounds and derivatives with another anti-retroviral agent. It further relates to their use in assays as reference compounds or as reagents.