P-cadherin antibodies

The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The invention also relates to heavy and light chain immunoglobulins derived from human P-cadherin antibodies and nucleic acid...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BAUER CHRISTOPHER TODD, BOURNER MAUREEN JERI, CASPERSON GERALD FRIES
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The invention also relates to heavy and light chain immunoglobulins derived from human P-cadherin antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human P-cadherin antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention.