Increased Expression of microRNA-17 Predicts Poor Prognosis in Human Glioma

Increased Expression of microRNA-17 Predicts Poor Prognosis in Human Glioma

Aim. To investigate the clinical significance of microRNA-17 (miR-17) expression in human gliomas. Methods. Quantitative real-time polymerase chain reaction (qRT-PCR) analysis was used to characterize the expression patterns of miR-17 in 108 glioma and 20 normal brain tissues. The associations of mi...

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Veröffentlicht in:BioMed research international 2012, Vol.2012 (2012), p.1-6
Hauptverfasser: Liang, Zhaohui, Ma, Shucheng, Geng, Shaomei, Wang, Shuai, Lu, Shengkui, Jiao, Baohua
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Sprache:eng
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Zusammenfassung:Aim. To investigate the clinical significance of microRNA-17 (miR-17) expression in human gliomas. Methods. Quantitative real-time polymerase chain reaction (qRT-PCR) analysis was used to characterize the expression patterns of miR-17 in 108 glioma and 20 normal brain tissues. The associations of miR-17 expression with clinicopathological factors and prognosis of glioma patients were also statistically analyzed. Results. Compared with normal brain tissues, miR-17 expression was significantly higher in glioma tissues (P
ISSN:2314-6133
2314-6141
DOI:10.1155/2012/970761