Can iga, C3, il-6 and TNF-α act as predictors for reoccurrence of breast cancer among Iraqi women?

Blood samples were collected from 30 women with age ranged from 27–70 years after 3 cycles of chemotherapy. Sera were used for IgA, IgG, IgM, C3, C4, IL-6 and TNF-a estimation. After 3 cycles of chemotherapy, all the immunological parameters reduced except TNF-a. Patients who developed disease reoccurrence after chemotherapy exhibit a significantly higher IgA, C3, IL-6 and TNF-a levels after 3 cycles of chemotherapy than patients who did not (p , 0.05). Therefore, serum IgA, C3, IL-6 and TNF-a can be used as predictors for breast cancer reoccurrence.