Fibrinolysis in idiopathic menorrhagia

Objective: the role of fibrinolysis in idiopathic dysfunctional uterine bleeding (IDUB). Design: prospective clinico-haematological study. Setting: patients were collected in Albatool maternity teaching hospital; a haematological study was conducted in Ibn Sina teaching hospital in Mosul from 10th January to 10th of June 2004. Participants: 53 patients with mean age of 40.5 years and a range of 15-54 years, complaining of idiopathic dysfunctional uterine bleedings(IDUB) served as experimental group, and 30 presumed healthy women served as a control group, their ages were between 18-45years. After exclusion of organic causes, drugs, IUCD, medical causes, and bleeding tendency, blood samples were tested for haemoglobin, plasma D-dimer test and plasma fibrinogen. Results: D-dimer test was positive in 16 out of 53 cases (30.2%) of experimental group (Group 1). It was significantly positive (p< 0.005) in cases of idiopathic menorrhagia compared to the control group. D-dimer test was significantly positive in those with prolonged duration of vaginal bleeding >7days, compared to those with heavy periods and short duration of vaginal bleeding (p