CMV infection among HIV / AIDS patients in Iraq

Background : The aim of the study was to determine the prevalence of CMV infection among HIV / AIDS patients in relation to disease progression, and to study the mortality during the period of the study. Patients and Methods : The study included 155 HIV/AIDS patients (148 HIV-infected and seven AIDS...

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Veröffentlicht in:Journal of the Faculty of Medicine, Baghdad Baghdad, 2006, Vol.48 (4), p.407-409
Hauptverfasser: al-Izzi, Sana M. H., al-Diwan, Jawad K., al-Hadithi, Tariq S., Urir, Ali R.
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Sprache:eng
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Zusammenfassung:Background : The aim of the study was to determine the prevalence of CMV infection among HIV / AIDS patients in relation to disease progression, and to study the mortality during the period of the study. Patients and Methods : The study included 155 HIV/AIDS patients (148 HIV-infected and seven AIDS patients) and 122 apparently "healthy" controls. CMV (IgG and 1gM) antibodies were determined by ELISA. The patients were followed up for a period of nine months, and retested frequently for development of active CMV infection. Results : The prevalence of CMV (IgG) antibodies in the HIV/AIDS patients was 100 %. A significant higher prevalence of CMV (IgM) among AIDS patients (42.9° / 6) than among HIV infected patients (0.0%) and "healthy" controls (0. 8 %). No deaths were reported among asymptomatic HIV infected patients while the mortality among AIDS patients was (42. 9 %). Only one patient (7. 7 %) out of 13 asymptomatic HIV infected developed active CMV infection 10 years later by testing for CMV (IgM) in 1991 and 2001. Conclusion : Demonstration of active CMV is of prognostic value in detection of development of AIDS and survival of patients.
ISSN:0041-9419
2410-8057