Helsinki computerized tomography scoring system can independently predict long-term outcome in traumatic brain injury

Abstract Objective The Helsinki computerized tomography (CT) scoring system was developed to predict long-term outcome in patients with traumatic brain injury (TBI) two years ago; however, it has not yet been external validated. This study aimed to determine whether this system could be used as an independent predictor for TBI. Methods This retrospective cohort study was performed on 302 consecutive patients with TBI. Univariate and multivariate logistic regressions and receiver operating characteristic (ROC) curve analyses were employed to determine the relationship between initial Helsinki CT scores and mortality and unfavorable neurological outcome at 6 months post-injury. Outcomes were assessed using the Glasgow Outcome Scale (GOS, scores of 1-3 defined as unfavorable outcome). Results Of all patients, mortality was 17.9% and unfavorable outcome was 41.4%. The Helsinki CT score was significantly associated with the 6-month outcome in univariate analyses (p