Sedation with α-2 agonist dexmedetomidine during unilateral subthalamic nucleus deep brain stimulation: a preliminary report
Highlights • We report a series of 11 consecutive patients who received Dex during unilateral STN-DBS between 2013 and 2014 • Eleven patients underwent unilateral STN-DBS with DEX sedation for advanced asymmetric PD • Micro-recordings from each microelectrodes were postoperatively analysed in order...
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| Veröffentlicht in: | World neurosurgery 2015 |
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| creator | Morace, Roberta, PhD De Angelis, Michelangelo, M.D Aglialoro, Emiliano, MD Maucione, Gianni, MD Cavallo, LuigiMaria, MD, PhD Solari, Domenico, MD Modugno, Nicola, MD Santilli, Marco Esposito, Vincenzo, MD |
| description | Highlights • We report a series of 11 consecutive patients who received Dex during unilateral STN-DBS between 2013 and 2014 • Eleven patients underwent unilateral STN-DBS with DEX sedation for advanced asymmetric PD • Micro-recordings from each microelectrodes were postoperatively analysed in order to confirm the presence of typical STN neuronal activity and its distribution along the trajectories. • In all patients micro-recordings revealed recognizable STN activity • The use of Dex allowed a quick and exhaustive assessment of any stimulation-related clinical improvement and side-effects. |
| doi_str_mv | 10.1016/j.wneu.2016.01.037 |
| format | Article |
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De Angelis, Michelangelo, M.D ; Aglialoro, Emiliano, MD ; Maucione, Gianni, MD ; Cavallo, LuigiMaria, MD, PhD ; Solari, Domenico, MD ; Modugno, Nicola, MD ; Santilli, Marco ; Esposito, Vincenzo, MD</creator><creatorcontrib>Morace, Roberta, PhD ; De Angelis, Michelangelo, M.D ; Aglialoro, Emiliano, MD ; Maucione, Gianni, MD ; Cavallo, LuigiMaria, MD, PhD ; Solari, Domenico, MD ; Modugno, Nicola, MD ; Santilli, Marco ; Esposito, Vincenzo, MD</creatorcontrib><description>Highlights • We report a series of 11 consecutive patients who received Dex during unilateral STN-DBS between 2013 and 2014 • Eleven patients underwent unilateral STN-DBS with DEX sedation for advanced asymmetric PD • Micro-recordings from each microelectrodes were postoperatively analysed in order to confirm the presence of typical STN neuronal activity and its distribution along the trajectories. • In all patients micro-recordings revealed recognizable STN activity • The use of Dex allowed a quick and exhaustive assessment of any stimulation-related clinical improvement and side-effects.</description><identifier>ISSN: 1878-8750</identifier><identifier>DOI: 10.1016/j.wneu.2016.01.037</identifier><language>eng</language><subject>Neurosurgery</subject><ispartof>World neurosurgery, 2015</ispartof><rights>Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4009,27902,27903,27904</link.rule.ids></links><search><creatorcontrib>Morace, Roberta, PhD</creatorcontrib><creatorcontrib>De Angelis, Michelangelo, M.D</creatorcontrib><creatorcontrib>Aglialoro, Emiliano, MD</creatorcontrib><creatorcontrib>Maucione, Gianni, MD</creatorcontrib><creatorcontrib>Cavallo, LuigiMaria, MD, PhD</creatorcontrib><creatorcontrib>Solari, Domenico, MD</creatorcontrib><creatorcontrib>Modugno, Nicola, MD</creatorcontrib><creatorcontrib>Santilli, Marco</creatorcontrib><creatorcontrib>Esposito, Vincenzo, MD</creatorcontrib><title>Sedation with α-2 agonist dexmedetomidine during unilateral subthalamic nucleus deep brain stimulation: a preliminary report</title><title>World neurosurgery</title><description>Highlights • We report a series of 11 consecutive patients who received Dex during unilateral STN-DBS between 2013 and 2014 • Eleven patients underwent unilateral STN-DBS with DEX sedation for advanced asymmetric PD • Micro-recordings from each microelectrodes were postoperatively analysed in order to confirm the presence of typical STN neuronal activity and its distribution along the trajectories. • In all patients micro-recordings revealed recognizable STN activity • The use of Dex allowed a quick and exhaustive assessment of any stimulation-related clinical improvement and side-effects.</description><subject>Neurosurgery</subject><issn>1878-8750</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqlT0tOw0AUmwVIVNALdPUukDCT0CRiwQaB2Jd99Jo82hcmL9F8KF1wKC7CmZgiblBvbEu2JSu1Mjo32lS3Q34QinmRdK5Nrsv6Qi1MUzdZU6_1lVp6P-iE0tw1dblQXxvqMfAkcOCwh5_vrADcTcI-QE-fI_UUppF7FoI-OpYdRGGLgRxa8HEb9mhx5A4kdpaiTy2aYeuQBXzgMdq_-XtAmB1ZHlnQHcHRPLlwoy7f0Hpa_vO1enh-en18ySiZDybXdpaFO7TvdCQ_TNFJyrWm9UWr283p2OmXqbQ2RVmVZw_8AtaNafc</recordid><startdate>2015</startdate><enddate>2015</enddate><creator>Morace, Roberta, PhD</creator><creator>De Angelis, Michelangelo, M.D</creator><creator>Aglialoro, Emiliano, MD</creator><creator>Maucione, Gianni, MD</creator><creator>Cavallo, LuigiMaria, MD, PhD</creator><creator>Solari, Domenico, MD</creator><creator>Modugno, Nicola, MD</creator><creator>Santilli, Marco</creator><creator>Esposito, Vincenzo, MD</creator><scope/></search><sort><creationdate>2015</creationdate><title>Sedation with α-2 agonist dexmedetomidine during unilateral subthalamic nucleus deep brain stimulation: a preliminary report</title><author>Morace, Roberta, PhD ; 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| subjects | Neurosurgery |
| title | Sedation with α-2 agonist dexmedetomidine during unilateral subthalamic nucleus deep brain stimulation: a preliminary report |
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