Sedation with α-2 agonist dexmedetomidine during unilateral subthalamic nucleus deep brain stimulation: a preliminary report

Sedation with α-2 agonist dexmedetomidine during unilateral subthalamic nucleus deep brain stimulation: a preliminary report

Highlights • We report a series of 11 consecutive patients who received Dex during unilateral STN-DBS between 2013 and 2014 • Eleven patients underwent unilateral STN-DBS with DEX sedation for advanced asymmetric PD • Micro-recordings from each microelectrodes were postoperatively analysed in order...

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Veröffentlicht in:World neurosurgery 2015
Hauptverfasser: Morace, Roberta, PhD, De Angelis, Michelangelo, M.D, Aglialoro, Emiliano, MD, Maucione, Gianni, MD, Cavallo, LuigiMaria, MD, PhD, Solari, Domenico, MD, Modugno, Nicola, MD, Santilli, Marco, Esposito, Vincenzo, MD
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Sprache:eng
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Neurosurgery
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Zusammenfassung:Highlights • We report a series of 11 consecutive patients who received Dex during unilateral STN-DBS between 2013 and 2014 • Eleven patients underwent unilateral STN-DBS with DEX sedation for advanced asymmetric PD • Micro-recordings from each microelectrodes were postoperatively analysed in order to confirm the presence of typical STN neuronal activity and its distribution along the trajectories. • In all patients micro-recordings revealed recognizable STN activity • The use of Dex allowed a quick and exhaustive assessment of any stimulation-related clinical improvement and side-effects.
ISSN:1878-8750
DOI:10.1016/j.wneu.2016.01.037