Hepatitis C virus (HCV) and human T-cell lymphotropic virus type 1 (HTLV-1) coinfection: Impact on liver disease, virological markers and neurological outcome

Hepatitis C virus (HCV) and human T-cell lymphotropic virus type 1 (HTLV-1) coinfection: Impact on liver disease, virological markers and neurological outcome

Highlights • Frequency of neurological abnormalities is unaltered during HCV/HTLV-1 coinfection. • Hepatic damage is reduced during HCV/HTLV-1 infection, even without HCV clearance. • Coinfection with HCV does not change HTLV-1-directed CD4+ T-cell proliferation. • HCV-related thrombocytopenia is re...

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Veröffentlicht in:International journal of infectious diseases 2017
Hauptverfasser: Espíndola, Otávio M, Vizzoni, Alexandre G, Lampe, Elisabeth, Andrada-Serpa, Maria José, Araújo, Abelardo Q.C, Leite, Ana Claudia C
Format: Artikel
Sprache:eng
Schlagworte:
Infectious Disease
Pulmonary/Respiratory
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Zusammenfassung:Highlights • Frequency of neurological abnormalities is unaltered during HCV/HTLV-1 coinfection. • Hepatic damage is reduced during HCV/HTLV-1 infection, even without HCV clearance. • Coinfection with HCV does not change HTLV-1-directed CD4+ T-cell proliferation. • HCV-related thrombocytopenia is reversed during coinfection with HTLV-1.
ISSN:1201-9712
DOI:10.1016/j.ijid.2017.01.037