Gastrointestinal Toxicity, Systemic Inflammation and Liver Biochemistry in Allogeneic Haematological Stem Cell Transplantation

Highlights • IL6 day +7 was associated with elevated bilirubin levels 1 month post-HSCT • Higher citrulline levels day +21 post-HSCT correlated with lower bilirubin levels 3 months post-HSCT • IL6 day +7 post-HSCT was associated with the occurrence of sinusoidal obstruction syndrome • Liver toxicity is associated with an increased inflammatory response mounted during the phase of maximal gastrointestinal toxicity in the early post-HSCT phase