Hematopoietic Stem Cell Transplantation Using Preimplantation Genetic Diagnosis and HLA Typing for HLA-Matched Sibling Donor: a Turkish Multicenter Study

Highlights • PGD with HLA matching involves selection of healthy and HLA identical embryos to the patient. • This should be considered for patients who need HSCT but lack an HLA identical donor. • HSCT using PGD and HLA typing for MSD is a successful and feasible method.

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Veröffentlicht in:Biology of blood and marrow transplantation 2017
Hauptverfasser: Kurekci, Emin, MD, Küpesiz, Alphan, MD, Anak, Sema, MD, Öztürk, Gülyüz, MD, Gürsel, Orhan, MD, Aksoylar, Serap, MD, Ileri, Talia, MD, Kuşkonmaz, Barış, MD, Eker, Ibrahim, MD, Cetin, Mualla, MD, Karasu, Gülsün Tezcan, MD, Kaya, Zühre, MD, Fışgın, Tunç, MD, Ertem, Mehmet, MD, Kansoy, Savaş, MD, Yeşilipek, Mehmet Akif, MD
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Sprache:eng
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Zusammenfassung:Highlights • PGD with HLA matching involves selection of healthy and HLA identical embryos to the patient. • This should be considered for patients who need HSCT but lack an HLA identical donor. • HSCT using PGD and HLA typing for MSD is a successful and feasible method.
ISSN:1083-8791
DOI:10.1016/j.bbmt.2017.02.002