External Validity of a Risk Stratification Score Predicting Early Distant Brain Failure and Salvage Whole Brain Radiotherapy after Stereotactic Radiosurgery for Brain Metastases

External Validity of a Risk Stratification Score Predicting Early Distant Brain Failure and Salvage Whole Brain Radiotherapy after Stereotactic Radiosurgery for Brain Metastases

Abstract Background A scoring system using pre-treatment factors was recently published ( Press et al., Cancer 2015) for predicting risk of early (≤6 months) distant brain failure (DBF) and salvage whole brain radiotherapy (WBRT) after stereotactic radiosurgery (SRS) alone. Four risk factors were id...

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Veröffentlicht in:International journal of radiation oncology, biology, physics biology, physics, 2017
Hauptverfasser: Press, Robert H, Boselli, Danielle M, Symanowski, James T, Lankford, Scott P, McCammon, Robert J, Moeller, Benjamin J, Heinzerling, John H, Fasola, Carolina E, Burri, Stuart H, Patel, Kirtesh R, Asher, Anthony L, Sumrall, Ashley L, Curran, Walter J, Shu, Hui-Kuo G, Crocker, Ian R, Prabhu, Roshan S
Format: Artikel
Sprache:eng
Schlagworte:
Hematology, Oncology and Palliative Medicine
Radiology
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Zusammenfassung:Abstract Background A scoring system using pre-treatment factors was recently published ( Press et al., Cancer 2015) for predicting risk of early (≤6 months) distant brain failure (DBF) and salvage whole brain radiotherapy (WBRT) after stereotactic radiosurgery (SRS) alone. Four risk factors were identified: (1) lack of prior WBRT, (2) melanoma or breast histology, (3) multiple brain metastases, and (4) total volume of brain metastases
ISSN:0360-3016
DOI:10.1016/j.ijrobp.2017.03.012