Specific combinations of Ca2+ channel inhibitors reduce excessive Ca2+ influx as a consequence of oxidative stress and increase neuronal and glial cell viability in vitro

Highlights • The effects of combinations of Ca2+ channel inhibitors on H2 O2 stressed cells were assessed in vitro. • Most combinations of inhibitors with oxATP decreased Ca2+ influx and increased cell viability. • However, reductions in intracellular Ca2+ concentration were not always linked to cell viability. • Combinations of inhibitors preserved some cell subpopulations, particularly NG2+/olig2- glia. • The data increase understanding of the efficacy of Ca2+ channel inhibitor combinations in vivo.