Development of Peptidomimetic Inhibitors of a Newly Isolated Atrial Peptide-Degrading Enzyme

Toll et al. recently reported the isolation of a new atrial peptide-degrading enzyme (ADE) from bovine kidney that preferentially cleaves atrial peptide substrates at their Ser-Phe bond. ADE is inhibited by general protease inhibitors that inhibit either metallo or cysteine proteases. However, it is...

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Hauptverfasser: Almquist, Ronald G, Olsen, Cris, Hiebert, Charles K, Kadambi, Srinivasa R, Brandt, Susan
Format: Report
Sprache:eng
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