Ventilation-Perfusion Relationships Following Experimental Pulmonary Contusion

Ventilation-perfusion changes after right-sided pulmonary contusion (PC) in swine were investigated by means of the multiple inert gas elimination technique (MIGET). Anesthetized swine (injury, n = 8; control, n = 6) sustained a right-chest PC by a captive-bolt apparatus. This was followed by a 12-m...

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Hauptverfasser: Batchinsky, Andriy I, Weiss, William B, Jordan, Bryan S, Dick Jr, Edward J, Cancelada, David A, Cancio, Leopoldo C
Format: Report
Sprache:eng
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Zusammenfassung:Ventilation-perfusion changes after right-sided pulmonary contusion (PC) in swine were investigated by means of the multiple inert gas elimination technique (MIGET). Anesthetized swine (injury, n = 8; control, n = 6) sustained a right-chest PC by a captive-bolt apparatus. This was followed by a 12-ml/kg hemorrhage, resuscitation, and reinfusion of shed blood. MIGET and thoracic computed tomography (CT) were performed before and 6 h after injury. Published in the Journal of Applied Physiology, v103 p895-902, 2007.