An Overview of the Technical Basis of HENRE 2.0 Models

This report provides an overview of the technical and scientific basis of the models incorporated in the Health Effects from Nuclear and Radiological Environments (HENRE) code for casualty estimation. The approach for each new model developed for HENRE included is presented. The models from HENRE include blast injury criteria models which are included in the Basic Casualty Estimation tool and the physiologically-based mathematical models included in the Advanced Casualty Estimation tool. In the discussion of the later tool, the aim is to provide the physiological basis for the mechanistic models included in HENRE and to highlight their application and value in casualty estimation, such as in the application to understanding the pathophysiological interactions of combined injury. The original document contains color images. Contract no. DTRA01-03-D-0014