Combined Injury Modeling: Radiation and Burn Workshop Report

This report provides an overview of the DTRA-sponsored workshop on combined injury (CI) modeling held on June 22, 2010. During this workshop, a panel of subject matter experts assembled by Applied Research Associates discussed acute radiation injury combined with thermal injury. Participants provide...

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Bibliographische Detailangaben
Hauptverfasser:	Stricklin, Daniela, Pellmar, Terry, Oldson, Darren, Millage, Kyle
Format:	Report
Sprache:	eng
Schlagworte:	ACUTE RADIATION SICKNESS Anatomy and Physiology BURNS(INJURIES) COMBINED INJURIES CUTANEOUS INJURIES EXPOSURE(PHYSIOLOGY) FLASH BURNS INTERACTIONS LETHALITY MATHEMATICAL MODELS MECHANISTIC MODELS ORGAN SYSTEM EFFECTS PARAMETERS PATHOPHYSIOLOGY RADIATION INJURIES RADIATION SICKNESS Radiobiology RESPONSE(BIOLOGY) SEVERITY THERMAL INJURIES WEAPONS EFFECTS Weapons Effects(biological) WOUNDS AND INJURIES
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Beschreibung
Zusammenfassung:	This report provides an overview of the DTRA-sponsored workshop on combined injury (CI) modeling held on June 22, 2010. During this workshop, a panel of subject matter experts assembled by Applied Research Associates discussed acute radiation injury combined with thermal injury. Participants provided input on the primary organ systems affected by CI, underlying mechanisms associated with CI, modeling approaches, recommended tools, and possible simplifying assumptions for modeling radiation injury combined with burn. Workshop participants also noted gaps in knowledge and potential paths forward. Workshop outcomes include a diagram that illustrates key pathophysiological processes associated with radiation injury and burn; these processes are primary candidates for modeling efforts. The original document contains color images.