Multi-Array (trademark) Immunodetection of Biowarfare Agents Using the Meso Scale Discovery (trademark) Sector PR (trademark)

Current bioanalysis roadmap supports an integrated approach for detection and identification using multiple technologies. The multi-array immunodetection system presented combines state-of-the-art immunoassay analysis (ORIGEN ECL) and nucleic acid analysis (SmartCycler Taqman). The briefing discusse...

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Hauptverfasser:	Lee, Fred, Menking, Deborah, Hamel, Joseph, Mangaya, Kishna, Myers, Emily, Goode, Michael, Zulich, Alan
Format:	Report
Sprache:	eng
Schlagworte:	ANTIGENS BIOANALYSIS Biochemistry BIOLOGICAL AGENT DETECTORS BRIEFING CHARTS Chemical, Biological and Radiological Warfare COMPONENT REPORTS Electricity and Magnetism ELECTROCHEMILUMINESCENCE ELECTROCHEMISTRY ELECTROLUMINESCENCE IMMUNOASSAY Medical Facilities, Equipment and Supplies Medicine and Medical Research NUCLEIC ACID ANALYSIS NUCLEIC ACIDS Optical Detection and Detectors Physical Chemistry SYMPOSIA
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Beschreibung
Zusammenfassung:	Current bioanalysis roadmap supports an integrated approach for detection and identification using multiple technologies. The multi-array immunodetection system presented combines state-of-the-art immunoassay analysis (ORIGEN ECL) and nucleic acid analysis (SmartCycler Taqman). The briefing discusses four 15-min washed assays developed for use on the Sector PR, a bioassy platform from Meso Scale Discovery. Assay protocols have been developed for both washed and nonwashed formats. The nonwashed format is currently in development. Prepared in collaboration with Geo-Centers, Inc., Aberdeen Proving Grounds, MD. Presented at the Joint Service Scientific Conference on Chemical & Biological Defense Research (5th) held at Hunt Valley, MD on 17-20 Nov 2003. See also ADM001851, Proceedings of the Joint Service Scientific Conference on Chemical & Biological Defense Research, 2003. The original document contains color images.