Collaborative Research and Support of Fitzsimmons Army Medical Center DWH Research Program Projects. Simultaneous Transmission/Emission Protocol (STEP) for Attenuation Correction of Breast and Diaphragmatic Attenuation Artifacts During SPECT 99mTc-SESTAMIBI Myocardial Perfusion Scans in Women Without Coronary Artery Disease

In a substantial percentage of women, current non-invasive tests, lack both sensitivity and specificity for determining the presence of coronary artery disease and prognosis. Myocardial perfusion imaging with radio- pharmaceuticals significantly increases both sensitivity and specificity of exercise...

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Bibliographische Detailangaben
Hauptverfasser:	Hayes, Robert L, Bennion, Scott, Lambert, Albert T
Format:	Report
Sprache:	eng
Schlagworte:	Anatomy and Physiology ARMY FACILITIES ARMY RESEARCH ATTENUATION CAD(CORONARY ARTERY DISEASE) CORONARY ARTERIES CORONARY DISEASE DIAPHRAGMS(ANATOMY) DWH RESEARCH PROGRAM FITZSIMMONS ARMY MEDICAL CENTER MAMMARY GLANDS Medicine and Medical Research MYOCARDIUM PERFUSION RADIOPHARMACEUTICALS SOFT TISSUES STEP(SIMULTANEOUS TRANSMISSION/EMISSION PROTOCOL) WOMEN
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Zusammenfassung:	In a substantial percentage of women, current non-invasive tests, lack both sensitivity and specificity for determining the presence of coronary artery disease and prognosis. Myocardial perfusion imaging with radio- pharmaceuticals significantly increases both sensitivity and specificity of exercise testing studies. However, attenuation artifacts in woman continue to cause false positive results. Until recently, attenuation artifacts(from breast,diaphragm, bone and soft tissue), the greatest cause of false positive studies, could not be corrected. A very Promising and significant recent development is the STEP protocol, whereby attenuation can be corrected by means of application of an attenuation map to radionuclide perfusion data.