Hyperthermia Impairs Retention of an Overtrained Spatial Task in the Morris Water Maze
Fifteen rats were trained to learn the location of a spatially fixed platform hidden in a Morris water maze (40 + or - 2 C). Then retention of the spatial task was assessed immediately after raising core body temperature (T sub c) to 42, 40 or 37 C (the normothermic control). The hyperthermic treatm...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Report |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Rauch, T M Welch, D I Gallego, L |
| description | Fifteen rats were trained to learn the location of a spatially fixed platform hidden in a Morris water maze (40 + or - 2 C). Then retention of the spatial task was assessed immediately after raising core body temperature (T sub c) to 42, 40 or 37 C (the normothermic control). The hyperthermic treatment order was counterbalanced according to a Latin-square design. Hyperthermia at 42 C T sub c significantly impaired the retention of spatial performance. Hyperthermic animals were cooled to normothermia (T sub c = 37 C) and spatial performance tested again. Recooling resulted in a complete recovery of spatial performance. These results demonstrate that hyperthermia-induced amnesia can be obtained on an overtrained spatial mapping strategy and recooling initiates recovery of spatial performance. Keywords: Retention psychology. |
| format | Report |
| fullrecord | <record><control><sourceid>dtic_1RU</sourceid><recordid>TN_cdi_dtic_stinet_ADA201064</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ADA201064</sourcerecordid><originalsourceid>FETCH-dtic_stinet_ADA2010643</originalsourceid><addsrcrecordid>eNqFjLsKwkAQRbexEPUPLO4PCPGBffBBLIKgQcswJBMcTDZhdhD0693C3uoW55w7drfsPbDag7UTwqkbSDTgwsbepPfoG5DH-RUdJfFc4zqQCbUoKDwhHrFF3qtKwJ2MFTl9eOpGDbWBZ7-duPnxUOyyRW1SlcHik5XpPl0ly2S7Wf_BX6zfNf4</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>report</recordtype></control><display><type>report</type><title>Hyperthermia Impairs Retention of an Overtrained Spatial Task in the Morris Water Maze</title><source>DTIC Technical Reports</source><creator>Rauch, T M ; Welch, D I ; Gallego, L</creator><creatorcontrib>Rauch, T M ; Welch, D I ; Gallego, L ; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA</creatorcontrib><description>Fifteen rats were trained to learn the location of a spatially fixed platform hidden in a Morris water maze (40 + or - 2 C). Then retention of the spatial task was assessed immediately after raising core body temperature (T sub c) to 42, 40 or 37 C (the normothermic control). The hyperthermic treatment order was counterbalanced according to a Latin-square design. Hyperthermia at 42 C T sub c significantly impaired the retention of spatial performance. Hyperthermic animals were cooled to normothermia (T sub c = 37 C) and spatial performance tested again. Recooling resulted in a complete recovery of spatial performance. These results demonstrate that hyperthermia-induced amnesia can be obtained on an overtrained spatial mapping strategy and recooling initiates recovery of spatial performance. Keywords: Retention psychology.</description><language>eng</language><subject>ANIMALS ; BODY TEMPERATURE ; CORES ; HYPERTHERMIA ; MAPPING ; PE61102A ; PLATFORMS ; Psychology ; RATS ; RECOVERY ; RETENTION(PSYCHOLOGY) ; SPATIAL DISTRIBUTION ; STRATEGY ; Stress Physiology ; TRAINING ; WUDA0C6122</subject><creationdate>1988</creationdate><rights>Approved for public release; distribution is unlimited.</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,778,883,27554,27555</link.rule.ids><linktorsrc>$$Uhttps://apps.dtic.mil/sti/citations/ADA201064$$EView_record_in_DTIC$$FView_record_in_$$GDTIC$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Rauch, T M</creatorcontrib><creatorcontrib>Welch, D I</creatorcontrib><creatorcontrib>Gallego, L</creatorcontrib><creatorcontrib>ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA</creatorcontrib><title>Hyperthermia Impairs Retention of an Overtrained Spatial Task in the Morris Water Maze</title><description>Fifteen rats were trained to learn the location of a spatially fixed platform hidden in a Morris water maze (40 + or - 2 C). Then retention of the spatial task was assessed immediately after raising core body temperature (T sub c) to 42, 40 or 37 C (the normothermic control). The hyperthermic treatment order was counterbalanced according to a Latin-square design. Hyperthermia at 42 C T sub c significantly impaired the retention of spatial performance. Hyperthermic animals were cooled to normothermia (T sub c = 37 C) and spatial performance tested again. Recooling resulted in a complete recovery of spatial performance. These results demonstrate that hyperthermia-induced amnesia can be obtained on an overtrained spatial mapping strategy and recooling initiates recovery of spatial performance. Keywords: Retention psychology.</description><subject>ANIMALS</subject><subject>BODY TEMPERATURE</subject><subject>CORES</subject><subject>HYPERTHERMIA</subject><subject>MAPPING</subject><subject>PE61102A</subject><subject>PLATFORMS</subject><subject>Psychology</subject><subject>RATS</subject><subject>RECOVERY</subject><subject>RETENTION(PSYCHOLOGY)</subject><subject>SPATIAL DISTRIBUTION</subject><subject>STRATEGY</subject><subject>Stress Physiology</subject><subject>TRAINING</subject><subject>WUDA0C6122</subject><fulltext>true</fulltext><rsrctype>report</rsrctype><creationdate>1988</creationdate><recordtype>report</recordtype><sourceid>1RU</sourceid><recordid>eNqFjLsKwkAQRbexEPUPLO4PCPGBffBBLIKgQcswJBMcTDZhdhD0693C3uoW55w7drfsPbDag7UTwqkbSDTgwsbepPfoG5DH-RUdJfFc4zqQCbUoKDwhHrFF3qtKwJ2MFTl9eOpGDbWBZ7-duPnxUOyyRW1SlcHik5XpPl0ly2S7Wf_BX6zfNf4</recordid><startdate>19881104</startdate><enddate>19881104</enddate><creator>Rauch, T M</creator><creator>Welch, D I</creator><creator>Gallego, L</creator><scope>1RU</scope><scope>BHM</scope></search><sort><creationdate>19881104</creationdate><title>Hyperthermia Impairs Retention of an Overtrained Spatial Task in the Morris Water Maze</title><author>Rauch, T M ; Welch, D I ; Gallego, L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-dtic_stinet_ADA2010643</frbrgroupid><rsrctype>reports</rsrctype><prefilter>reports</prefilter><language>eng</language><creationdate>1988</creationdate><topic>ANIMALS</topic><topic>BODY TEMPERATURE</topic><topic>CORES</topic><topic>HYPERTHERMIA</topic><topic>MAPPING</topic><topic>PE61102A</topic><topic>PLATFORMS</topic><topic>Psychology</topic><topic>RATS</topic><topic>RECOVERY</topic><topic>RETENTION(PSYCHOLOGY)</topic><topic>SPATIAL DISTRIBUTION</topic><topic>STRATEGY</topic><topic>Stress Physiology</topic><topic>TRAINING</topic><topic>WUDA0C6122</topic><toplevel>online_resources</toplevel><creatorcontrib>Rauch, T M</creatorcontrib><creatorcontrib>Welch, D I</creatorcontrib><creatorcontrib>Gallego, L</creatorcontrib><creatorcontrib>ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA</creatorcontrib><collection>DTIC Technical Reports</collection><collection>DTIC STINET</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Rauch, T M</au><au>Welch, D I</au><au>Gallego, L</au><aucorp>ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA</aucorp><format>book</format><genre>unknown</genre><ristype>RPRT</ristype><btitle>Hyperthermia Impairs Retention of an Overtrained Spatial Task in the Morris Water Maze</btitle><date>1988-11-04</date><risdate>1988</risdate><abstract>Fifteen rats were trained to learn the location of a spatially fixed platform hidden in a Morris water maze (40 + or - 2 C). Then retention of the spatial task was assessed immediately after raising core body temperature (T sub c) to 42, 40 or 37 C (the normothermic control). The hyperthermic treatment order was counterbalanced according to a Latin-square design. Hyperthermia at 42 C T sub c significantly impaired the retention of spatial performance. Hyperthermic animals were cooled to normothermia (T sub c = 37 C) and spatial performance tested again. Recooling resulted in a complete recovery of spatial performance. These results demonstrate that hyperthermia-induced amnesia can be obtained on an overtrained spatial mapping strategy and recooling initiates recovery of spatial performance. Keywords: Retention psychology.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_dtic_stinet_ADA201064 |
| source | DTIC Technical Reports |
| subjects | ANIMALS BODY TEMPERATURE CORES HYPERTHERMIA MAPPING PE61102A PLATFORMS Psychology RATS RECOVERY RETENTION(PSYCHOLOGY) SPATIAL DISTRIBUTION STRATEGY Stress Physiology TRAINING WUDA0C6122 |
| title | Hyperthermia Impairs Retention of an Overtrained Spatial Task in the Morris Water Maze |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T11%3A41%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-dtic_1RU&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=unknown&rft.btitle=Hyperthermia%20Impairs%20Retention%20of%20an%20Overtrained%20Spatial%20Task%20in%20the%20Morris%20Water%20Maze&rft.au=Rauch,%20T%20M&rft.aucorp=ARMY%20RESEARCH%20INST%20OF%20ENVIRONMENTAL%20MEDICINE%20NATICK%20MA&rft.date=1988-11-04&rft_id=info:doi/&rft_dat=%3Cdtic_1RU%3EADA201064%3C/dtic_1RU%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |