The Mutagenic Potential of (E)-1,2,3,4-Tetrahydro-6-methyl-1-(2-methyl-1-oxo-2-butenyl) Quinoline (CHR 5)

The mutagenic potential of (E)-1,2,3,4-tetrahydro-6-methyl-1-(2-methyl-1-oxo-2-butenyl) quinoline (CHR 5) was assessed by using the Ames salmonella/Mammalian Microsome Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538 were exposed to doses ranging from .1 mg/plate to 3.2...

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Hauptverfasser: Sauers,Leonard J, Fruin,John T
Format: Report
Sprache:eng
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Zusammenfassung:The mutagenic potential of (E)-1,2,3,4-tetrahydro-6-methyl-1-(2-methyl-1-oxo-2-butenyl) quinoline (CHR 5) was assessed by using the Ames salmonella/Mammalian Microsome Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538 were exposed to doses ranging from .1 mg/plate to 3.2 x .00005 mg/plate. It was determined that the test substance did not have mutagenic potential.